Longevity · Answer
Can you lower your biological age?
Quick answer
Can you lower your biological age?
Research suggests you can influence your biological age. People with healthier habits tend to have younger biological-age estimates, and a small 2021 pilot trial reported lower epigenetic age after an 8-week diet and lifestyle program. The evidence is still early, but the habits involved — not smoking, exercise, diet, sleep and moderate alcohol — reliably support longer, healthier lives.
At a glance
Key takeaways
- Biological age estimates how old your body seems; it can differ from chronological age.
- A 2021 pilot trial reported a 3.23-year reduction in epigenetic age versus controls after 8 weeks — promising but small.
- Adopting five low-risk lifestyle factors was linked with 12–14 extra years of life expectancy at age 50.
- No supplement or protocol can guarantee a younger biological age.
Your chronological age only moves in one direction. Your biological age — an estimate of how old your body seems based on markers of health and function — appears to be more flexible.
What the research shows
Healthy habits track with healthy aging. A large 2018 study of U.S. adults found that people who followed five low-risk lifestyle factors — never smoking, a healthy body weight, regular physical activity, a healthy diet and moderate alcohol intake — had a life expectancy at age 50 about 14 years longer for women and 12 years longer for men than people who followed none.
Epigenetic age may shift. In a 2021 pilot randomized trial, 43 healthy men followed an 8-week program of diet, exercise, sleep and relaxation guidance. The intervention group's epigenetic-age estimate fell by about 3.2 years relative to controls. It's a small, short study that needs replication — but it suggests biological-age markers can respond to lifestyle.
How is biological age measured?
Researchers use epigenetic clocks such as Horvath's multi-tissue clock and PhenoAge, which combine DNA methylation patterns or blood biomarkers into an age estimate. Results vary between tests, so trends over time are more meaningful than any single number. Learn more in our biological age guide.
Where to start
- Don't smoke — the single biggest modifiable factor. More in our longevity habits guide.
- Move daily and train strength at least twice a week.
- Eat mostly whole foods with plenty of plants and adequate protein.
- Protect 7–9 hours of sleep.
- Keep alcohol low.
See where you stand with the free biological age calculator.
People also ask
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Citations
Sources & references
- [1]Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trialFitzgerald KN, Hodges R, Hanes D, et al.. Aging (Albany NY), 2021 · Pilot trialView source : Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial (opens in a new tab)
- [2]Impact of healthy lifestyle factors on life expectancies in the US populationLi Y, Pan A, Wang DD, et al.. Circulation, 2018 · Cohort studyView source : Impact of healthy lifestyle factors on life expectancies in the US population (opens in a new tab)
- [3]DNA methylation age of human tissues and cell typesHorvath S. Genome Biology, 2013 · Laboratory studyView source : DNA methylation age of human tissues and cell types (opens in a new tab)
- [4]An epigenetic biomarker of aging for lifespan and healthspanLevine ME, Lu AT, Quach A, et al.. Aging (Albany NY), 2018 · Cohort studyView source : An epigenetic biomarker of aging for lifespan and healthspan (opens in a new tab)
Study links open a PubMed search for the exact title, so they keep working even if a journal changes its URL.
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