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Genetics glossary

What is CYP1A2?

Quick answer

CYP1A2: definition

CYP1A2 is a liver enzyme responsible for metabolizing most of the caffeine you consume; genetic variants influence whether you clear caffeine faster or slower.

CYP1A2, explained

The rs762551 variant is commonly used to classify people as “fast” or “slow” caffeine metabolizers. Smoking, some medications, pregnancy and oral contraceptives also affect CYP1A2 activity.

Why it matters

Knowing your tendency can help you time caffeine to protect sleep and avoid jitters.

Learn more

FAQ

CYP1A2 FAQs

What is CYP1A2?

CYP1A2 is a liver enzyme responsible for metabolizing most of the caffeine you consume; genetic variants influence whether you clear caffeine faster or slower.

Why does CYP1A2 matter?

Knowing your tendency can help you time caffeine to protect sleep and avoid jitters.

Answers

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