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Genetics glossary

What is DNA methylation?

Quick answer

DNA methylation: definition

DNA methylation is the addition of methyl groups to DNA — usually at cytosine bases — which helps regulate whether genes are switched on or off without changing the DNA sequence.

DNA methylation, explained

It's a primary epigenetic mechanism and helps give each cell type its identity. DNA methylation patterns change with age, which is the basis of epigenetic clocks.

Why it matters

DNA methylation connects nutrition, lifestyle and aging — and is central to biological age testing.

Learn more

FAQ

DNA methylation FAQs

What is DNA methylation?

DNA methylation is the addition of methyl groups to DNA — usually at cytosine bases — which helps regulate whether genes are switched on or off without changing the DNA sequence.

Why does DNA methylation matter?

DNA methylation connects nutrition, lifestyle and aging — and is central to biological age testing.

Answers

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