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Genetics glossary

What is Methylation?

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Methylation: definition

Methylation is the transfer of a methyl group (one carbon and three hydrogens) onto DNA, proteins or other molecules; it regulates genes, recycles homocysteine and helps make neurotransmitters and creatine.

Methylation, explained

The body's main methyl donor is SAMe. Folate, B12, B6, riboflavin, choline and betaine keep the methylation cycle running.

Why it matters

Methylation touches gene expression, detoxification, mood, energy and aging.

Learn more

Genetics · GuideMethylation: What It Is, Why It Matters and How to Support ItWhat is methylation? A plain-English guide to the methylation cycle, the nutrients that power it (folate, B12, B6, choline), related genes like MTHFR and COMT, and how to support it.Genetics · GuideMTHFR: What the Gene Does, Common Variants and What Results MeanWhat is MTHFR? Learn what the gene does, how common the C677T and A1298C variants are, what results do and don't mean, folic acid vs. methylfolate, and smart next steps.Genetics · HubGenetic Testing for Wellness: The Complete GuideHow wellness genetic testing works, what methylation and nutrient genes can reveal, what DNA tests can't tell you, and how to turn a report into smarter daily habits.

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FAQ

Methylation FAQs

What is Methylation?

Methylation is the transfer of a methyl group (one carbon and three hydrogens) onto DNA, proteins or other molecules; it regulates genes, recycles homocysteine and helps make neurotransmitters and creatine.

Why does Methylation matter?

Methylation touches gene expression, detoxification, mood, energy and aging.

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