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Genetics glossary

What is Methylfolate?

Also known as: 5-MTHF, L-methylfolate.

Quick answer

Methylfolate: definition

Methylfolate (5-methyltetrahydrofolate) is the active form of folate that donates a methyl group to recycle homocysteine into methionine.

Methylfolate, explained

It is available as a supplement and bypasses the MTHFR conversion step required for folic acid. Whether it's preferable for an individual depends on labs, life stage and medications.

Why it matters

Methylfolate is central to discussions about MTHFR variants and folate supplementation.

Learn more

FAQ

Methylfolate FAQs

What is Methylfolate?

Methylfolate (5-methyltetrahydrofolate) is the active form of folate that donates a methyl group to recycle homocysteine into methionine.

Why does Methylfolate matter?

Methylfolate is central to discussions about MTHFR variants and folate supplementation.

Answers

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